Generally, it is recommended that Dritho-Scalp be applied once a day or as directed by a physician. Anthralin is known to be a potential skin irritant. The irritant potential of anthralin is directly related to each patient's individual tolerance. Therefore, where the response to anthralin treatment has not previously been established, always commence treatment using a short contact time of 5 to 10 minutes for at least one week using Dritho-Scalp. Contact time can be increased stepwise to twenty to thirty minutes, or as directed by a physician, before removing the cream by thoroughly washing or showering. Apply as directed by a physician. The optimal period of contact will vary according to the patient's response to treatment. To open the tube, unscrew the cap and invert to pierce the membrane. Comb the hair to remove scalar debris and, after suitably parting, apply Dritho-Scalp only to the lesions and rub in well, taking care to prevent the cream spreading onto the forehead. Keep Dritho-Scalp well away from the eyes. Avoid application of the cream to uninvolved scalp margins. Remove any unintended residue which may be deposited behind the ears. At the end of each period of contact, wash the hair and scalp to remove any surplus cream (which may have become red/brown in color). Always wash hands thoroughly after use. Store at controlled room temperature, 15-30C (59-86F).